Tramadol VS Hydrocodone | Which One Is Better?

Tramadol VS Hydrocodone | Which One Is Better?

Opioid analgesics are a class of strong painkillers that include Tramadol vs Hydrocodone. They are frequently employed to treat mild to severe pain, including persistent pain brought on by cancer or other chronic illnesses. Injuries and surgical pain can also be treated with them. When nonopioid painkillers like ibuprofen and acetaminophen have failed to provide relief from severe persistent pain, hydrocodone is prescribed.

Your brain is significantly affected by these medicines. Although they both function in various ways, they are both quite effective. These medications also have their own set of negative effects. Here are some similarities and differences between Tramadol vs Hydrocodone, along with which one is better.

What Is Tramadol?

What is Tramadol?
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A strong painkiller Tramadol is used to treat moderate to severe pain that is not being treated by other painkillers. A synthetic opioid, tramadol operates on the brain and spine (central nervous system) to lessen pain perception.

Tramadol is available in an extended-release formulation for the continuous management of pain. Tramadol in this form should not be used to treat pain as needed.


To take the appropriate dose of Tramadol (unless prescribed by your physician), here is what you need to know.

  • For Normal Pain: 50 mg to 100 mg (maximum 400 mg for severe pain) taken orally every four to six hours.
  • For Chronic Pain: 100 mg (300 mg for severe pain) per day taken orally.

Tramadol Side Effects

Your breathing may slow down or stop when using tramadol, which has the potential to become habit-forming. Misuse of this medication, particularly in children or other people taking it without a prescription, has the potential to result in addiction, overdose, or even death. Keep this medication out of the reach of others.

Tramadol should not be prescribed to children and teens under 18. Moreover, it should not be given to anyone who has recently undergone surgery. 

Tramadol usage during pregnancy may result in the baby experiencing potentially fatal withdrawal symptoms.

If you combine this medication with alcohol or other medications that slow your breathing or make you drowsy, fatal adverse effects may result.

Read More: What Are The Tramadol Side Effects In Elderly

What Is Hydrocodone?

What Is Hydrocodone?
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One of the most common opioid painkillers is Hydrocodone.

The extended-release hydrocodone medications Zohydro ER and Hysingla ER are used to relieve severe pain round-the-clock.

Hydrocodone with extended-release (ER) should not be taken for pain on an as-needed basis.

Hydrocodone Dosage

How much Hydrocodone you should consume depends on which variant the doctor has prescribed you. There are two variants available:

  • Zohydro Capsule: 10 mg consumed orally twice every day. 
  • Hysingla Tablet: 20 mg consumed orally once every day.

Hydrocodone Side Effects

Opioid medication misuse can lead to addiction, overdose, or death. The drug should be kept out of the reach of others.

If you are pregnant, let your doctor know. The mother used hydrocodone while she was pregnant, and the withdrawal symptoms might be life-threatening for the baby.

If you combine opioid medications with alcohol, other sedatives, or substances that slow your breathing, you run the risk of experiencing fatal adverse effects.

Tramadol VS Hydrocodone: Which One Should You Take?

Tramadol VS Hydrocodone: Which One Should You Take?
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If you wish to know who is the winner of the fight between Tramadol Vs Hydrocodone, then the answer is – it depends on the severity of the pain. 

Most of the time, doctors will at first prescribe you Tramadol. This is because between the two, Tramadol is the milder medicine. However, if you have severe pain, then the doctor might prescribe Hydrocodone.

How They Work

Tramadol and hydrocodone both bind to brain receptors to alter how you perceive pain. Tramadol, however, also extends the amount of time that norepinephrine and serotonin are accessible to your brain. This is thought to assist in blocking pain impulses in your spinal cord.

Tramadol VS Hydrocodone: What If I Overdose?

Tramadol vs Hydrocodone: What If I Overdose?
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If you or anyone close to you happens to overdose on Tramadol or Hydrocodone, they will require immediate medical help. Call 911 or get in contact with the nearest hospital that you know of. Some of the known symptoms of an overdose are severe drowsiness, breathlessness, and palpitated pupils. Fainting and loss of consciousness are two of the most evident symptoms. 

While it might take a while for help to arrive, check if the person is breathing or not. If not, conduct Cardiopulmonary Resuscitation (CPR) if you can.

In addition, keep Naloxone in the house, which is a potent anti-opioid. It may be pre-prescribed by your doctor if you are on opioids. 

Frequently Asked Questions (FAQs):

People that have been prescribed opioids for pain relief have several questions regarding Tramadol vs Hydrocodone. Here are my answers to these questions.

Q1. Does Tramadol Have The Same Strength As Hydrocodone?

Ans. While both have similar levels of strength, Hydrocodone is slightly stronger than Tramadol. Therefore, doctors will prescribe Tramadol for less severe pain. On the other hand, they will prescribe hydrocodone for severe pain.

Q2. What Is A Stronger Pain Reliever Than Tramadol?

Ans. Oxycodone is one of the best and most potent pain relievers that you can afford right now. Even though Tramadol will be prescribed by doctors most of the time due to it being relatively less potent, Oxycodone is way stronger.

Q3. Is Tramadol Stronger Than Opiates?

Ans. Tramadol is actually one of the least potent variants of an opioid. On the other hand, there are various other opiates, like Hydrocodone and Oxycodone, that are far more potent.

Final Verdict: Tramadol VS Hydrocodone – Which Is Better?

Discuss all underlying medical concerns with your doctor before learning about Tramadol vs Hydrocodone. List all of your dietary supplements, prescription drugs, and over-the-counter meds. If you’ve ever struggled with alcoholism or drug abuse, let your doctor know.

With your doctor, go about the potential advantages and drawbacks of this and other opioids. You and your partner can decide on the least effective pain relief option.

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Debamalya Mukherjee

Debamalya is a professional content writer from Kolkata, India. Constantly improving himself in this industry for more than three years, he has amassed immense knowledge regarding his niches of writing tech and gaming articles. He loves spending time with his cats, along with playing every new PC action game as soon as possible.

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