Trental Tablet, Extended Release – Uses, Side Effects, and More

Trental Tablet

Trental tablet? 

Have you been prescribed this one by your doctor recently? 


Are you thinking about taking medication for a particular health condition because one of your known individuals has suggested it to you? 


Know a little more about this “Trental Tablet, Extended Release” before you place an order for this medicine. Here, in this article, I will cover all the necessary information about the Trental 400mg tablet. 

From its formulation to usage to side effects, in this article, you will get all the information you need. Still, I will ask you to consult your doctor and not take any medicine without having proper knowledge about it. 

Doctors have a degree; they got the degree after studying for years, and also, you might not know what your body is going through and how any particular medicine will react to others. 

That is why I will also talk about the interaction of Trental with some other medicines as well. So, now, let’s start the discussion by getting some basic knowledge about Trental. 

What Is Trental? 

What Is Trental 

Trental is basically used for improving blood flow along with reducing some particular symptoms of a condition named intermittent claudication. As we all know, diseases can be cured, but when it comes to health conditions, they can not be cured completely. 

The same goes for here as well. Trental 400mg is not at all capable enough to cure this specific condition. It just helps in improving blood flow, and as a result, your blood can carry oxygen to your organs and tissues. 

Trental Tablet, Extended Release: Ingredients

Trental Tablet, Extended Release Ingredients

When you are looking for information about a particular tablet, it is crucial to know the ingredients of the medicine. 

Trental contains 400 mg of active drugs along with the following inactive drugs. 

  • Hypromellose USP. 
  • Polyethylene glycol NF.
  • FD&C Red No. 3.
  • Magnesium stearate NF.
  • Titanium dioxide USP.
  • Talc USP.
  • Povidone USP.
  • Hydroxyethyl cellulose USP.

Trental Tablet, Extended Release: Uses

Trental Tablet, Extended Release Uses

Trental is being used in order to improve the symptoms of some particular blood flow-related issues in arms or legs that are addressed as intermittent claudication as a result of occlusive artery disease. 

Here, I like to mention that Pentoxifylline can also decrease muscle pain, aching, or cramps during exercise such as walking. It usually occurs with intermittent claudication. 

Pentoxifylline is one of those drugs that are known for being hemorheological agents. By assisting in blood flow more easily through all those narrowed arteries, this agent usually works. As a result, the amount of oxygen automatically increases in the blood and can be delivered when the muscles require more oxygen.  

How To Use Trental 400mg?

How To Use Trental 400mg

You need to take this medication with your food, generally 3 times a day or as instructed by your doctor. Never crush or chew this medication. If you do so, it can release all of the drugs at once and will increase the side effects. 

There are already several side effects; you do not want to have more severe ones on your plate. 

Also, never split or break the tablet unless it has a score line and your doctor is asking you to do so. You need to swallow the entire tablet or split the tablet (only if your doctor says) without chewing or crushing it. 

The dosage of Trental might vary on the basis of your medical condition and also the response to your treatment. When you are already under this medication, I will recommend you to take this medicine on a regular basis as your doctor has prescribed to get the best from it.

Even if you are feeling well, do not discontinue taking this medicine without consulting with your doctor. Usually, the improvements in symptoms take place in 2 to 4 weeks, but it might take up to 8 weeks in order to get the full benefit of Trental. 

Warning: Before You Take It

Warning Before You Take It

So, now, you know the use and also the ingredients that Trental has. Here I would like to guide you about the side effects and also the things you should know about before you actually take a dose of it. 

In case you have any recent bleeding in the retina of your eye or in your brain, I will ask you not to take any dose of this medicine. And also, obviously, if you are allergic to Trental, theophylline, such as uniphyl, theolair, therchron, slo-bid, theo-dur, theo-24, elixophyllin and others, or caffeine, you should not take this medicine. 

In order to be on the safe side, you should inform your doctor about the following health conditions in case you have them. These are the situations when you must avoid taking Trental. 

  • Heart disease.
  • Kidney or liver disease. 
  • Coronary artery disease or hardened arteries. 
  • History of stroke or heart attack. 
  • A history of bleeding inside your eye or brain. 
  • An intestinal or stomach ulcer
  • In case you are under any medication for preventing or treating blood clots. 
  • In case you are also using theophylline. 
  • In case you recently had surgery. 

In case you are pregnant or planning to get pregnant, you also should inform your doctor about that while he is prescribing your trental 400. It is because of the effect of Trental on an unborn baby. 

Also, it is crucial to note that Pentoxifylline might pass into breast milk and might also harm your baby when you are nursing him. It means you should not breastfeed your baby when you are using Pentoxifylline. 

What Should Your Trental Dosage be? 

What Should Your Trental Dosage be

The extended release of one trental tablet’s usual dosage is 400 mg three times a day with meals. And the usual recommended treatment generally continues for a minimum of 8 weeks. 

Supplements, Substances, Or Drugs Interact With Trental

There are some substances or drugs with which Trental might interact. Here they are. 

  • Theophylline.
  • Blood thinners. 
  • Oxtriphylline.
  • Dyphylline.
  • Aminophylline. 

At the same time, tobacco consumption can worsen your condition or might lessen the beneficial effects of Trental extended-release, and that too by narrowing your blood vessels. In case you are into tobacco, I will ask you to consult with your doctor and also mention all the medications you are already using. 

Trental Dosage During Breastfeeding or Pregnancy

Trental Dosage During Breastfeeding or Pregnancy

As I have mentioned earlier, the effects of Trental on the unborn are still unknown. Only in case you are being prescribed, go for this medicine. Apart from that, do not even think about taking that when you are pregnant or planning to conceive

Also, it might pass into your breast milk. So, if you are nursing your baby, consult with your doctor before taking any. 

Trental Side Effects

Trental Side Effects

Now, I will inform you about the most common side effects of Trental. Now, without wasting any more time, let’s get to know them. 

  • Headache.
  • Dizziness.
  • Upset stomach.
  • Belching.
  • Gas.
  • Vomiting.
  • Nausea. 
  • Blurred vision.
  • Flushing (redness, tingly feeling, or warmth).

In case you are experiencing some serious side effects of Trental, you should inform your doctor about the same. The list of serious trental side effects includes the following. 

  • Pink or red urine. 
  • Feeling like you might pass out. 
  • Easy bleeding or bruising. 
  • An irregular or fast heartbeat. 
  • Chest pain. 
  • Vomiting or coughing up blood. 
  • Tarry or bloody stools. 

FAQs (Frequently Asked Questions)

When it is about any medicine and especially something like Trental, it is usual to have a lot of doubts. That is why now I am going to answer some of the most common questions I have been asked by my readers. 

I believe you might also want to know the answers to these questions. 

Q1: Does Trental Affect Blood Pressure?

Ans: The action of antihypertensive agents might get potentiated by Trental. Patients who are taking this particular medication have to be under blood pressure monitoring.

Q2: What Happens If I Miss A Dose?

Ans: In case you have missed any dose, I would ask you to take the missed one as soon as you remember. And in case it is almost time for the next dose, skip the missed dose. Taking extra medicine to make up for the missed dose is a strict NO. 

Q3: Is Trental Considered A Blood Thinner?

Ans: Basically, Trental is a hemorheological agent. So practically, it can not be considered a blood thinner or anticoagulant like Eliquis. 

Q4: What Happens If I Overdose?

Ans: The overdose symptoms of Trental might include the following. 
⦿ Fever.
⦿ Agitation.
⦿ Drowsiness,
⦿ Fainting.
⦿ Flushing, such as a tingly feeling, redness, or warmth. 
In case you think that you might have overdosed, seek emergency medical attention or call the poison helpline.

To Conclude

I believe after going through this article; you get the information you were looking for. In case you still have any questions, you can ask that in the comment section. I will try to come up with a solution as soon as possible.

Till then, listen to your doctor. The professional knows exactly what is good for you and what is not.

Read Also About:

Leave a Reply

Your email address will not be published. Required fields are marked *

Related Posts